Semaglutide vs Tirzepatide, Cagrilintide, and Retatrutide: Mechanisms & Research Insights Cagrilintide, an amylin analogue, is a promising medication for weight loss by enhancing satiety, delaying gastric emptying, and suppressing appetite. In my patients, I have also seen increased Cagrilintide: Benefits, Dosage, and Weight Loss Potential Explained Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Zepbound Outperforms CagriSema in Head to Head Phase III Obesity Trial